Temporal range: Early Oligocene – Early Miocene
Antb 1999 pre ms1 x3 h253.jpg
A stamp of Plesictis
Scientific classification
Kingdom: Animalia
Phylum: Chordata
Class: Mammalia
Order: Carnivora
Superfamily: Musteloidea
Family: Mustelidae
Genus: Plesictis
Pomel, 1846

Plesictis is an extinct genus of mustelids (originally described as a procyonid) endemic to Europe during the Oligocene and Miocene 33.9—20.0 Ma existing for approximately 13.9 million years.

Plesictis was a 75 centimetres (2.46 ft) long animal, resembling a weasel with large eyes, or possibly a cacomistle. Its large eyes and very long tail suggest that it may have been nocturnal and arboreal. Judging from its teeth, it was an omnivore.